angina - spasmodic, choking or suffocating pain. a.aneurysm - a ballooning out of the wall of a blood vessel or a heart chamber due to a weakening of the wall by disease or injury.anencephaly - markedly defective development of the brain, cerebral hemispheres absent or reduced to small masses, together with absence of the bones of the cranium.anastomosis - a connection between two blood vessels or tubes.anaplasia - loss of differentiation of cells and of their orientation to one another and to their framework and blood vessels.anaphylaxis - the immediate immunologic (allergic) reaction initiated by the combination ofantigen (allergen) with mast cell cytophilic antobody (chiefly IgE). anaphylactic (adj) - as in anaphylactic shock - life threatening respiratory distress, vascular collapse and shock manifesting extremely great sensitivity to foreign protein or other material.analgesia ( analgesic) - the absence of pain removing pain.The associated disease states may be inflammatory, hereditary or neoplastic and the deposition may be local or generalized or systemic. amyloidosis - a group of conditions of diverse etiologies characterized by the accumulation of insoluble fibrillar proteins (amyloid) in various organs and tissues of the body - eventually organ function is compromised.amyloid light chain (AL) - a component of immunoglobulin, occurs in mulitple myeloma amyloid associated protein (AA) - derived from liver protein, occurs in reactive systemic amyloidosis amyloid familial (AF) - abnormal transthyretin. There are several precursor proteins which are then deposited in the tissue as amyloid e.g.Each fibril is composed of identical polypeptide chains arranged in stacked antiparallel beta-pleated sheets (this is what impar ts the characteristic birefringence under polarized light). Amyloid deposits are composed of straight, non-branching fibrils with a diameter of 7.5 to 10 nm and indefinite length.It is a waxy, amorphous, eosinophilic, hyalinelike material that exhibits red-green birefringence under polarized light when stained with Congo red. amyloid - the extracellular protein substance deposited in amyloidosis. ![]()
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